S.E.M.I. – Side Effects May Include… Free Download (Tenoke)

S.E.M.I. – Side Effects May Include… is an Action , Roguelike, Platformer game for PC published by Two Horn Unicorn in 2026.

S.E.M.I. – Side Effects May Include… PC Game 2026 Overview:

S.E.M.I. is a single-player and co-op action platformer with puzzle elements.

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Play as patients of an unusual clinic, take experimental drugs, interfere with each other, and be ready for chaos and unpredictable side effects! S.E.M.I. is a cooperative online game about escaping from a special clinic. Here, you and up to 3 of your brainless loyal friends play as patients, fighting staff and other patients while stumbling into all sorts of unexpected situations. Brawls, side-effect pills, and brutal platforming will absolutely challenge your clumsy friends’ hands sense of teamwork in S.E.M.I. – Side Effects May Include.

Expect obstacles, puzzles, deadly traps, and rooms where a single wrong move can knock out the entire squad. Communicate in voice chat and arrange sabotage help your friends pass through rooms, get out of traps and fight with opponents! In your arsenal: close combat, physics, amazing abilities and … imagination! Madness is near! You and your friends can go crazy and start running, jumping and fighting, and your abilities will become uncontrollable.

Do you want to take back control? Take the pills 🙂 Locations are randomly generated from rooms with changing gravity, traps, moving walls, and other “pleasant” surprises. After a successful escape, you will receive a medical report: “The patient was stable until he started hitting the guards with a bottle. Diagnosis: Overmotivation” or something worse! Unlock new costumes and decorations. Let each new escape be more stylish than the previous one!

Features of S.E.M.I. – Side Effects May Include…:

  • Alice’s syndrome is either tiny or gigantic — have time to adjust!
  • Stendhal syndrome — are you looking at a painting? Now you’re hysterical and destroying everything around you!
  • Laser astigmatism — two sights, one laser… Where will he shoot?
  • Bipolar force is an invulnerable monster, then a helpless rag!

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Minimum System Requirements :

  • Requires a 64-bit processor and operating system
  • OS: Windows 10
  • Processor: Intel Core i5 series or Ryzen series
  • Memory: 8 GB RAM
  • Graphics: GTX 960 or AMD R9 290
  • DirectX: Version 11
  • Storage: 3 GB available space
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